Wednesday, May 16, 2018

IRIDOCORNEAL ENDOTHELIAL SYNDROMES: A primer

Iridocorneal Endothelial Syndromes (ICE) are characterized by the following:

Common features of the three ICES:

1. Corneal endothelial dystrophy
2. Distorted pupil
3. Ectropion uveae
4. Goniosynechiae
5. Secondary synechial glaucoma

Characteristics which distinguish between the three ICES:

1. Iris naevus syndrome (Cogan-Reese)=
Multiple small or a few larger iris nodules.

2. Chandler’s Syndrome=
Corneal oedema at normal or mildly elevated IOP.

3. Essential iris atrophy=
Progressive iris atrophy with iris hole formation (opposite to the side of goniosynechiae). 
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