Wednesday, June 8, 2016

THE BIOCHEMICAL MECHANISMS OF GLAUCOMATOUS NEURODEGENERATION

There is ample evidence from studies done at various laboratories world-wide, as well as, from clinical trials, that biochemical mechanisms play an important role in the causation of glaucomatous optic nerve degeneration (GOND).

These biochemical mechanisms include excitatory aminoacids, caspases, protein kinases, oxygen free radicals, nitric oxide, TNF alpha, neurotrophins and metalloproteins.
This is an article which covers the salient points of these mechanisms in brief.

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741173/

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GLAUCOMA AS A CENTRAL NEURODEGENERATIVE DISEASE

    The major length of the axon of the retinal ganglion cells (RGC) is extra-ocular, with pre-chiasmal, chiasmal and post-chiasmal compon...