Wednesday, July 4, 2018

IRIDOCORNEAL DYSGENESIS


Individuals with malformations of structures of the anterior segment of the eye frequently develop elevated intraocular pressure and glaucoma. This post takes a brief figurative look at some of these conditions which lead to developmental glaucomas.

1. POSTERIOR EMBRYOTOXON: Characterized by anterior displacement of Schwalbe's Line. 





2. AXENFELD ANOMALY: Characterized by posterior embryotoxon and peripheral iris strands.



3. RIEGER ANOMALY: Characterized by iris hypoplasia, correctopia and polycoria.



When Rieger anomaly is associated with systemic features such as: dental and facial defects e.g. maxillary hypoplasia; umblical abnormalities and pituitary involvement, it is called RIEGER SYNDROME
Association of Axenfeld anomaly and Rieger anomaly together is known as: AXENFELD-RIEGER SYNDROME.




4. PETER SYNDROME: Characterized by central or paracentral corneal opacity, absent Descemet's membrane and endothelial layers. There are also iridocorneal adhesions from the border of the central corneal opacity. Peter's anomaly is of 2 types. Type 1 is unilateral, while Type 2 is bilateral in about 60% cases with lens adherent to the posterior surface of the cornea due to lack of separation between the 2 layers. Type 2 is also associated with systemic features such as: short stature, mental retardation, abnormal ears, cleft lip and/or palate, defects of extremities, genitourinary system defects, cardiovascular anomalies, and gastrointestinal defects.

3 comments:

  1. Thanks to Prof Hommer for the correction.

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  2. Wow very impressive, keep up the great work

    ReplyDelete