IRIDOCORNEAL ENDOTHELIAL SYNDROMES: A primer
Iridocorneal Endothelial Syndromes (ICE) are characterized by the following:
Common features of the three ICES:
1. Corneal endothelial dystrophy
2. Distorted pupil
3. Ectropion uveae
5. Secondary synechial glaucoma
Characteristics which distinguish between the three ICES:
1. Iris naevus syndrome (Cogan-Reese)=
Multiple small or a few larger iris nodules.
2. Chandler’s Syndrome=
Corneal oedema at normal or mildly elevated IOP.
3. Essential iris atrophy=
Progressive iris atrophy with iris hole formation (opposite to the side of goniosynechiae).